Assuming you are a veterinarian, you may want to consider being slightly more professional in your communication Instead of taking the heat, paying what you owe for flapping your gums when you said you wouldnt, you took the easy way out. After taking my 4yo Yorkie off Apoquel 2 weeks ago, (see my comment on 8/21) my girls UPC and albumin have greatly improved. She is a young dog from a breeder with no history of seizures. Please listen to Dr. Jones. I also wonder if advantix 2 would be responsible for his rash. Both Apoquel and Zyrtec are effective at relieving allergy symptoms in dogs, so combining them may provide even more relief for your dog. I am going to let my Vet know. (Answered 2023), Is It Legal to Eat Dog Meat in Canada? As soon as I stop giving her apoquel the stomach problem stopped. I have also found that by wiping his feet with a damp towel after he comes in from outside, there is far less itching and scratching. Let these people talk about what they think about this drug. We all need to do our part to get this drug off the market. Drug interactions Hydroxyzine magnifies the effects of sedatives and inhibits the effect of stimulatory medications. After autopsy Im told he had tumor like growths in his chest. She almost immediately stopped itching and I was delighted. 1 [deleted] 8 yr. ago He came to us with terrible skin allergies. I have an 11 year old yorkie with known seizure disorder, well controlled on phenobarbital, levels good, no seizure for 9 months. 5.Essential Fatty Acid supplements. Have had my 20 month old westie on it for the last two weeks. I have taken him off of it for 3 weeks now due to low funds, and was going to put him back on them this weekend. I have read some of the negative comments here and all I can say is They destroyed his stomach, his stomach was trembling, he lost appetite on and off, the last day when he collapsed was because he was not able to breathe due to a mass near his heart coming from the spleen had formed from taking this SHIT. I have tried many things and 3 Vets, also already two operations. It is disturbing to realize that others have had almost the same situation. Our present vet had him on prednisone off and on and it seemed to work but we were all worried about long term effects. I cant wait to see what the blood work will reveal though, it will be interesting. Most veterinarians say no because both drugs can cause drowsiness. It works well for mild allergic reactions, such as an insect bite or sting. We have a small medical practice (my wife is med director.). Our friend was aware of the allergy and per her normal vet was doing a process of elimination with his food, treats, shampoo, etc. When I do find him upstairs he is comatose and has vomited all around the house and done a poo in the family room. The mechanism of action is thought to be similar to that of other Janus kinase inhibitors, which block the activity of Janus kinase enzymes, which are important in signal transduction in many cells, including those involved in the allergic response, she says. No, I dont think I will give it to him again. When we found the new vet he said he wanted to try Peatie on a new anti-itch drugpricey but effective. Then came the motor coordination hiccups. He weighs 12 pounds and the hydroxyzine was 10mg to be given twice a day. Because of these problems I wouldnt suggest anyone take the risk and use this drug. Someone called us today to ask if we knew more of this approach for her dog. My 10 year old Maltese 10 pound has had intermittent allergy problems his entire life. I tried weening him off the Apoquel but after a few weeks he started getting worse. Despite that, he continued to prescribe Apoquel for our dog until August 2018. I do not recommend this medication. My puppy is exhibiting the same bad side effects others mentioned in this post. The medication is available in tablet form in the following doses: 10 mg; 25 mg; and 50 mg. Not risking it !!! How long has this been a concern? Hello, I have 2 german shepherds. While the drug helped the itching slightly it did not stop it. Get Pippa's free dog training tips delivered to your inbox. Does that sound about right? DO NOT GIVE THIS MEDICINE TO YOUR ANIMAL. fluids and other meds He has intermittent hotspots and a rash. Dogs are able to take hydroxyzine. But it is not the only antihistamine that vets use. Ive been looking for others with the same diagnosis. My dog (66 lbs boxer/hound mix) is prescribed apoquel daily by her current vet for allergies. Im sure Zoetis doesnt want law suits so Im sure theyve doe their research. She is Am. My Chow has now been on Apoquel for less than 48 hours. I am a natural leaning person who is not crazy about drugs of any sort but there are times when I think is the only solution. Im concerned about his weight gainhes up to 36# which is big for a Frenchie. Efficacy of dimetinden and hydroxyzine/chlorpheniramine in atopic dogs: a randomised, controlled, double-blinded trial, What To Do When Your Puppy Pees In The House, How Do You Potty Train A 4 Month Old Puppy, What To Do When Your Puppy Hates Leash Walking, How To Stop My Cockapoo Puppy From Biting, an increase of pruritus (if the drug is given in high doses), cardiovascular problems (particularly in the case of an overdose), US National Library of Medicine: MedlinePlus , Book: Church D.B., Small Animal Clinical Pharmacology Elsevier Health Sciences, 2008. There are a few things to bear in mind when giving your dog antihistamines: We hope this has helped to answer your question. To all dog owners WARNING do not give your dog Apoquel . It contains essential fatty acids, probiotics, and colostrum, but more importantly it has helped thousands of dogs. Both need to go out more often to pee. After 5 days on Yes, Apoquel and Gabapentin can be used together for dogs - as there is no known interaction between the two drugs. After several trips to the vet,nothing was resolved. Told vet and she took bloods so fingers crossed. I certainly cant say for sure that the Apoquel caused this tumor but am quite confident that it probably exacerbated it. Something has to be done. Of the 247 dogs studied, 26 were removed for unknown reasons and 18 were euthanized. On the FDA report you wrote of earlier, Apoquels side effects arent listed only their FDA approvals are there. He seemed afraid to move, as if it caused him pain. It comes in tablet form and is given daily, providing relief for 24 hours. The vet told us anal gland problems can definitely be due to allergies. Yeh! Colostrum is taken away from baby calves and sold to supplement companies to make money, and the calves suffer. I just had my 14 year old westie Flo on Apoquel for 26 days. No they are not some very serious side effects have not been listed. I was never told this drug is an immunosuppressent. We need our own check list to take a survey on this drug. (Source: Cosgrove SB, Wren JA, Cleaver DM, et al. Can my dog take Apoquel and Zyrtec together? Additionally, Cytopoint was specifically created to target itch associated with atopic (environmental) allergies. Fuck this drug. For slight allergies try otc antihistamines like Zyrtec. I have noticed he has been very hungry and is peeing a lot. Apoquel is a drug that stops the itching sensation caused by dermatitis. I have had her and my other dogs on a special diet but it still doesnt help. Dr Jones. I am convinced that apoquel is the cause and I would like to know if his liver enzymes will return to normal now that apoquel has been stopped. Other veterinarians may have their short comings, but at least they are more concerned about their patients and less about their wallets. A vet gave my dog hydroxyzine because he was licking his paw a lot. Apnea means that the patient stops breathing temporarily. Monitor your dog for any symptoms. Hamish is very threadbare and I have been loathed to clip him. Antihistamines are over-the-counter so they have a . Michael (would be happy to share more in private with you.). Have you ever had to use hydroxyzine for dogs? It was attached to the muscle and she didnt cut into it because of the location of the tumor. I dont want my baby to have these terrible side effects I am reading about here. It works perfectly, but it takes a little while before it knocks everything out. The only thing the bw showed was that his body was basically starving. As soon as spring arrived, the scratching and paw licking began. Her liver enzymes, glucose reading were off the charts. I will never place another animal on a medication like this again. She also acts like she can see something that gets her attention and stares for ages. Dogs with the MDR1 genetic mutation can become very ill or die if given certain medications. so I went back to my regular vet I trusted who pit Ollie on ever increasing steroids to try to kill this yeast infection. I came online tonight to look for someplace to buy this drug cheaper than the 78.00 a month I was getting from the vet.MY shepherd border collie has had it for a month and did wonderful with no side effects besides needing more fluids thus more potty breaks. Hydroxyzine for dogs is a canine antihistamine. can respond inappropriately, and may begin attacking the Im wondering if anyone has had luck with a very low dose achieving less itching with less side effects? dogs to infection, inflammatory disease demodex mites, and Never again will I use that drug. Please share your comments. Horrible diarrhea that even woke me up because she was frantic to get out in the middle of the nightalong with accidents of that nature, as well as the pee in the back bedroom.. (thank goodness we have hardwood floors). She cant even find her toys unless I put them in her mouth. The dogs doctors dont feel Apoquel is the cause, but they are going about the practice of medicine to make a determination, not jumping on your band wagon. It was told to us in private that the long term effects of the Apoquel could be the cause of her cancer. Carprofen is a non-steroidal anti-inflammatory drug (NSAID) that is used by veterinarians as a supportive treatment for the relief of arthritic symptoms in geriatric dogs. She examined him and told me that he was having a reaction to the hydroxyzine so dont give any more to him. I thought I had found relief for him and for us but obviously not. So, its impossible to recommend across the board dosages that will produce good results. Apoquel has made my dog awfully ill. We have spent so much money from the side effects of apoquel. We tried everything with no resolve. Still sweet and wants to play but, can hardly find the ball when it is right in front of her face. His nose is cold and his behavior is normal, but we are very worried. No more and I will be talking to my vet about this. It does seem that the shot and the baytril will make her infection go away and allergies better at least for awhile. Worst of all she has gone instantly blind. FDA approval of APOQUEL is based on results of two clinical trials conducted in the She couldnt eat on her own and worst, she didnt recognize us or let us pet her. While the exact mechanism of action is not known, it is thought that Apoquel works by inhibiting the activity of Janus kinase enzymes, which are important in signal transduction in many cells, including those involved in the allergic response. After two trips to the vet, then being referred to a specialists, we learned his liver enzymes were off the charts. Lastly, always check with your veterinarian before giving your dog any new medication, just to be on the safe side. About three days later after her last dose, she was finally starting to act herself again and soon began eating out of her bowl. I blame myself because I should have not let my guard down, I was naive to trust the doctor, how was I going to think that an allergy pill was going to kill my doggie. But by God she earned it become i g a vet is harder than med school I have two westies on apoquel, both have problem skin. I felt terrible because she was still itching during this battle with cancer so I kept her on the Apoquel. Euthanasia 12-5-2017. University) This is what I believe happened to my Baby Girl Thank you for any help. Apoquel never did stop the itching. seizure. Im convinced this drug killed my baby girl. In one long term study published by Apoquel's manufacturer Zoetis, they studied 247 dogs over the course of two years. Can you tell me a little more about the dog's situation? (Answered 2023). 2 days ago, on daily dosing st this point, he had another. As always, you should talk to your veterinarian before starting your dog on any new medication, even if its something as seemingly innocuous as Benadryl or Zyrtec. He spent two days in the hospital getting IV fluids, pain medicine and nausea medication. We had started a chemotherapy regimen in November which completely zapped her energy. She gave my dog Prince Si Miao Four Marvels Formula (can buy this online) I gave a 1/4 or less amount that a human would take for 4 months (herbs must be watched not to take for long periods of time so look for any side effects like blood in stool) . Saw right after I hit the Submit Comment button. Here are some dog owner experiences with it: http://www.2ndchance.info/Apoquel-Comments.htm. Or pups under 12 months old. He suffers from allergies also. Metacam with known renal and liver side effects. A typical dose is 1 mg per pound in dogs every 6-8 hours. Better safe than sorry. God knows how he pulled through but after 5 days he was on a turn in the right direction. We had tried everything, including allergy shots. I noticed she had to see alot, but only thought she was marking her spots. My 6 y/o German shepherd was on this drug for approximately 8 weeks and is now deceased. The chemical messengers which are being blocked by these drugs are involved in more processes than just controlling inflammationmost likely as yet undiscovered!!! Generally, a 7 to 10-day therapeutic trial will reveal if the treatment is going to work. I got him at six weeks old, so I can say I know him better than anyone. This medicine stopped the itch and it had wonderful results UNTIL recently she had 2 seizures!!!! Can you give a dog Zyrtec and Apoquel together? He had an ultrasound and it was determined it was likely due to the Apoquel, and he was diagnosed with liver disease. Two days ago (45 days into Apoquel) Peatie woke from a nap and walked around frantically bumping into things, hes blind, but it seemed more than usual, so I picked him up and he went tight in my armskind of like a dog stretching, but I soon realized he was in a seizure when he urinated all over me. Please everyone try Natural pet! Thanks everyone! IF your dog has allergies, he needs to be on these. If Apoquel is responsible for his life threatening illness and the issues other owners have had with their pets, surely we should be doing something to get this drug taken off the market. We had a lovely dog who frequently got ear infections and because of this drug we have no dog. With these tablets he not my normal fur baby. In his 10 years he has never defecated in the house. After six days our super energetic dog became extremely lethargic and will not eat, we stopped administering the drug. Vet in the practice, (not her regular vet) approached me in the lobby and said she had a drug that would stop her allergies. We went to the vet because she was quite lethargic. We decided to continue the Apoquel until the next vet visit which was about 1 week later. instead of the dull molting fur.that just wouldnt grow, When I woke up this morning, I could see that his condition had taken a turn for the worse. I have read your comments about your pets having side effects. I have three Shih Tzu on Apoquel for three months. After 3 days she is back to scratching, licking and bighting again with enflamed skin and a lot less energy. This was very traumatic to witness in a 200 lb.dog. If worse I will probably take her off it. Two days after being on Apoquel, we noticed less itching. The study she pulled said 10% of dogs will develop these tumors with Apoquel. I now wonder if he had environmental allergies. It may be used off label to treat skin infections in cats and urinary tract infections in dogs. Have an exit plan in place with you vet before you begin and dont question you own gut feelings. A dog who never once peed in the house, started having accidentswhen she was on a morning, noon, evening and bedtime schedule. This is also holistic and works by making the yeast exit the body through the hair follicles. I stoped it todayim terrified. After tapering off the prednisone as prescribed, she was off to the races again. Its going to be hard to give up a prescription that has made such a difference for our girl, but I also know that our vet has her best interest in mind. I even had to duct tape socks to his feet. When we told the vet we wanted to discontinue this because of the side effects she acted like she has never heard of anyone having hear issues before. My 7 year old male GSD has been on apoquel for 2+ years now for horrible scratching due to atopic dermatitis. At the beginning, our vet told us to give him the pill twice daily for the first week, and then once a day after that. After one week on BID dosing he had a 5min seizure, I just chalked it up to stress. Heres a handy chart to help you figure out the right dosage for your pup: Mutasim is an author and software engineer from the United States, I and a group of experts made this blog with the aim of answering all the unanswered questions to help as many people as possible. I went back to the vet and did an allergy test where we found out he is allergic to 19 things, including fish which was what he was eating. For example, it can counteract the effects of warfarin. Please never use acepromazine for dogs. If the wind blows the wrong way she starts breaking out. Gabapentin is a medication that veterinarians are prescribing with increasing frequency, sometimes alone but more commonly in combination with other medications, for the management of pain in dogs. Today Im contacting the FDA to self report these side effects. I dont want her to be itchy, but I also dont want her to be dead. E-mail: rfisher1951@yahoo.com However, after only 5 days on the drug, he became lame with a painful right paw and a painful back leg. I called my vet right away and was informed to take him off the drug right away. Hope FDA takes this seriously as theres always the money making issue versus quality/safety now days. The hot topic in the world of dermatology right now is Apoquel.Apoquel is an exciting new medication for the treatment of allergic itching in dogs. Fourth Quarter 2014 Adjusted Net Income of $203 Million, or Adjusted Diluted EPS1 hospitalization for the diagnosis and treatment of pneumonia (after 91 days), and one dog We are back to trying to find the right balance to make life more comfortable. They assumed that he must have a tumor, so, we scheduled an Ultrasound. BTW, we cleaned up her diet and such, but some of the natural remedies suggested above are almost impossible to administer to my dog. What Does Altered Dog Mean? Cetirizine Hydrochloride for Dogs. I AM STOPPING THIS MED TODAY! But for cases of severe pruritus, many still prefer hydroxyzine. Just curious? After reading almost all of the comments on here I would think you would all exchange info and file a Class Action Lawsuit against the makers of this drug, the FDA for negligence, at least. Like everyone else it helped make her more comfortable at first then increased eating and lethargy. She had a check up and we were told everything was good. My 8 year old beagle/basset was put on Apoquell for itching on 10/13/16 and died this morning from liver failure and pancreatitis. 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